Theoretical Model and Characteristics of Mitochondrial Thermogenesis

نویسنده

  • Jian-Sheng Kang
چکیده

Based on the first law of thermodynamics and thermal diffusion equation, the thermal physical model of thermogenesis for brown adipocyte is deduced. The model settles the long-standing questioning about the ability of raising cellular temperature by endogenous thermogenesis, and explains the thermogenic characteristics of brown adipocyte. The model and calculations also suggest that the number of free available proton is the major limiting factor for endogenous thermogenesis and its speed.

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تاریخ انتشار 2017